Abstract

Bilateral retinal venous occlusion and retinal neovascularisation were diagnosed in a 48 years old male patient. He had pulmonary and cerebrovascular events, It was thought that a decrease of activated protein C resistance may be present. After excluding vasoocclusive diseases, we searched for the levels of protein C, protein S and presence of activated protein C resistance. Low levels of activated protein C resistance are considered to be related to 'familial venous thromboembolism'. A relation is found among arterial and venous thrombosis, recurrent spontaneous abortions, cerebrovascular occlusion, acute myocard infarction and activated protein C resistance. The presence of activated protein C resistance in a young patient with sudden vision loss, retinal arterial and venous occlusion and retinal neovascularisation may be helpful to confirm the diagnosis.