Abstract

Introduction: Bilateral acute depigmentation of the iris is a new condition characterized by pigment dispersion in the anterior chamber, iris depigmentation and lack of inflammatory components. We report two female cases aged 24 and 22 years who presented with redness, pain, photophobia and diagnosed as bilateral acute depigmentation of the iris.

Cases: Ocular examinations of two cases were similar. Bilateral pigment precipitates on the cornea endothelium, pigment deposition in the anterior chamber and diffuse iris depigmentation from collarette to iris root were seen. In gonioscopic examination of patients, there was diffuse pigment deposition in the trabecular meshwork. Inflammatory cells in aqueous humour, posterior synechiae, transillumination defect or pigment deposition on anterior capsule of lens weren’t detected. After eight month follow-up, iris repigmentation started. A new iris nevus was formed on the right eye of Case 1.

Comment: Bilateral acute depigmentation of the iris may be misdiagnosed as iridocyclitis and the conditions with pigment dispersion or iris atrophy. Bilateral acute depigmentation of the iris should be thought for differential diagnosis of these conditions.