Abstract

In the treatment of cancer, immunotherapy is applied to retrieve more precisely targeted activities from the components of immune systems via development of treatments mimicking immune system. To this end investigators in the field of oncology have conducted many studies concerning immunotherapy. Cancer cells lead a relatively more independent, and uncontrolled life with their ability to evade from immune system when compared with normal cells. Blockade of the checkpoint has opened the way for a new targeted treatment modalities. In this paper we will briefly review potential position of anti-PD-1, and anti-PD-L1 as novel, and very popular treatment approaches in cancer.