Abstract

OBJECTIVE: We aimed to compare the effıciency of intravenous esmolol, remifentanil and tramadol in control of the hemodynamic response occuring during laryngoscopy and intubation in ENT surgery. MATERIAL AND METHOD: The 60 cases who participated in the study were randomly separated into 3 groups. Esmolol 2 mg/kg to the fırst group (Group E), remifentanil 1 ug/kg to the second group (Group R), tramadol 2 mg/kg to the third group (Group T) was applied intravenously. On the second minute following the administration of the drug in 15 seconds, induction was carried on with 4-6 mg/kg thiopental and 0.5 mg/kg atracurium. On the 2nd minute post-induction, laryngoscopy and intubation was perfonned. The HR, SAP, and DAP values occuring during pre-induction and intubation and until the 1Oth min. post-intubation were measured with one min. intervals. THE FINDINGS: Difference between the groups in respect of demographic properties was not found. In our study, in all groups, the pre-intubation HR and arterial pressures were found signifıcantly lower according to the basai values (p<0,05). In the fırst 3 min. Following laryngoscopy and intubation, the HR and arterial pressure values were unchanged in the esmolol and remifentanil groups, while these parameters were found signifıcantly higher in the tramadol group (p<0,05). CONCLUSION: The bolus doses of esmolol and remifentanil were efficient in similar extent in prevention of hemodynamic responses due to laryngoscopy and intubation, however, 2 mg/kg tramadol is insufficient in suppressing the hemodynamic response.