Abstract

Objective: Evaluation of oocyte cryopreservation cycles and results that we perform for various indications in our clinic.

Methods: The patients aged between 18-48 years and subjected oocyte cryopreservation for various indications between 2015 and 2020 in tertiary referral center hospital in vitro fertilization clinic were investigated in this retrospective study. The groups are established as single women for fertility preservation before gonadotoxic treatments, single women with diminished ovarian reserve, whose sperm could not be obtained on the day of oocyte retrieval or oocyte pooling due to microinjection application on the same day for the whole oocytes.

Results: According to the data obtained from oocyte freezing after controlled ovarian hyperstimulation cycles of 224 patients for various indications; oocyte survival rate was 92.68%, pregnancy rate was 8.66% and live birth rate was 4.66% per oocyte thaw cycle.

Conclusion: In oocyte cryopreservation cycles that have taken their place in clinical practice, oocyte survival rates after freeze-thaw were found quite high with vitrification method; pregnancy rates and live birth rates obtained with these oocytes were found similar to embryo freeze-thaw rates. By the developments in vitrification techniques, it is thought that oocyte freeze-thaw cycles which have high survival and success rates will have stronger place in the field of assisted repruductive treatments.