Abstract

Aim: To evaluate the recovery profiles and postoperative adverse events after general anesthesia with desflurane and sevoflurane in childhood adenotonsillectomy. Material and Methods: Fiftyfour children, ASA physical status I, underwent conventional cold tonsillectomy and curettage adenoidectomy under general anesthesia with desflurane (n = 27) and sevoflurane (n =27) were evaluated retrospectively. Anesthesia recovery, eye opening, postoperative vomiting, coughing and laryngospasm were compared for two anesthetic regimens. Findings: The mean age was 6+0.41 (min-max: 3-11, 11 female, 16 male) in desflurane group and 6+0.46 (min-max: 3-12, 9 female, 18 male) in sevoflurane group. No significant difference was observed between the two groups in terms of age, gender, body mass index and operation duration (p>0.05) The mean time to eye opening following desflurane was 3.3+0.3 (1.3 - 7.5) minutes versus 6.3+0.5 (2.5-10.5) minutes following sevoflurane, difference was statistically significant (p=0.03, p<0.05). Recovery of both agent is similar, 35.56 minutes in desflurane 34.67 minutes in sevoflurane (p=0.07, p>0.05). There was no statistical difference in the postoperative vomitting, coughing, and laryngospasm, among two groups. P values were 0.55, 0.48, and 0.15 respectively. Conclusion: The occurrence of recovery and adverse events between desflurane and sevoflurane were not significantly different, except that the eye opening duration after anesthesia was significantly shorter in desflurane group.