Abstract

Introduction:

The incidence of bacteraemia after transplantation is changes between 8.6-26 % depending on the type of the organ. And the bacteraemia is seen as the most important factor for mortality and morbidity. This situation has importance especially for the multi-drug resistant bacteria. In this group, Pseudomonas infections are seen as the most fatal pathogens but donor derived pseudomonas infections are very rare.

It is showed that Pseudomonas infections may cause pseudo aneurysm and disruption in the arterial anastomosis in early post-transplant period. This condition may result with graft loss or patient death.

Case:

Pseudomonas Aeruginosa microbial growth in respiratory tract was detected in A multi-trauma patient in Intensive Care Unit. According to culture-antibiogram results, appropriate antibiotherapy ( cephalosporine-sulbactam + colistine) was introduced. At the day 7 of the treatment, and day 19 of hospitalization, brain death occurred and patient was offered as a deceased organ donor.

Pseudomonas aeruginosa microbial growth was detected in 43 yr old, male, kidney recipient and appropriate treatment was begun. At the post-transplant day 13, due to arterial interruption, graft nephrectomy was performed. One week after discharge, patient had complains of pain and skin lesions in his lower extremity. Vaso-occlusive pathology was not determined. On follow up, septic shock was developed and micro-abscess focuses in lung paranchima was revealed. Decortication and right upper lobectomy was performed. At post-operative day 3, post-transplant day 89, patient died due to respiratory failure and sepsis.

Comment:

Using the required microbiological follow up and treatment facilities, utilization of organs from infected donors is possible, but in this situation, especially multi-drug resistance micro-organisms should be kept in mind. In this pathogens, donor derived pseudomonas infections are important with high mortality rates.