Abstract

INTRODUCTION

To assess the characteristics of patients with upper non-variceal gastrointestinal system bleeding (NVUGISB).

METHODS

141 cases with NVUGISB who were referred to the Tepecik Research and Training Hospital, Emergency Department, between 01 08 2013 ile 01 08 2014 and examined by endoscopy in the Gastroenterolgy and Internal Medicine Department were assessed. Demographical characteristics, etiology and risk factors were determined.

RESULTS

The mean age of the 141 patients was 63,2+17,3 (20-103) years, of whom 97 (68,8 %) were male and 44 ( 31,2 %) female. Of the patients, 36 ( 25,5 %) were smokers, 21 (14.9%) drank alcohol, 39 ( 27,7 %) had used acetyl salicylic acid (ASA), 51 ( 36,2 %) had used non-steroidal anti-inflammatory drug (NSAID) and 13 ( 9,2 %) had used clopidogrel, 13 ( 9,2 %) had used warfarin, 3 ( 2,1 %) had used new generation oral anticoagulant and 8 ( 5,7 %) had used Proton pump inhibitor. When the co-morbid diseases had been evaluated; hypertension(55 patients, 39 %), coronary artery disease (33 patients, 23.4%), diabetes mellitus (27 patients, 19,1%), chronic renal failure cerebrovascular accident history (16 patients, 11,3 %), and malignancy (13 patients, 9,2%) were determined. The first three most common causes of bleeding detected by endoscopy were duodenal ulcer (45%), gastric ulcer (25%) and antral gastritis (19%).

DISCUSSION AND CONCLUSION

Duodenal ulcer was found as the most common cause of NVUGISB in this study. Bleeding is seen in the elderly more commonly and advanced age, co-morbid diseases and drugs used ( NSAID etc) increase the mortality.