Factors Associated With Short And Long-Term Graft Survival And Their Predictors In Kidney Transplantation
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VOLUME: 22 ISSUE: 3
P: 139 - 145
2012

Factors Associated With Short And Long-Term Graft Survival And Their Predictors In Kidney Transplantation

Anatol J Gen Med Res 2012;22(3):139-145
1. Tepecik Eğitim ve Araştırma Hastanesi, İç hastalıkları, Nefroloji Bölümü, İzmir
2. Şifa Üniversitesi, Tıp Fakültesi, İç Hastalıkları ABD, Nefroloji Bölümü, İzmir
3. Ege Üniversitesi Tıp fakültesi, İç Hastalıkları ABD, Nefroloji Bölümü, İzmir
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Received Date: 2015-05-18T16:24:12
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Abstract

Aim: The aim of this study was to identify the associated factors with short and long term graft survival and their predictors in renal transplantation which is the optimum treatment method for end-stage renal failure. Material and Method: Data of 400 patients who underwent renal transplantation at Ege University Organ Transplantation Unit were retrospectively investigated. Findings: The age, gender, primary kidney disease, weight before transplantation, blood transfusion, HCV serology, the type and duration of dialysis and number of transplantations for patients were primarily determined. Furthermore, the gender and age of donor, live-cadaver, ideal-marginal, haplotype or miss-match and duration of cold ischemia were also determined. Survival rates after exclusion of general graft survival and death were significant in ideal and elderly live-donor (p<0.02, p<0.01) and ideal and marginal cadaver (p<0.007, p<0.03) however, there was not significant relationship between elderly live and marginal cadaver (p<0.25, p>0.63). Conclusion: Although there are some problems for transplantations from marginal donors; they still have superior outcomes in terms of survival, life quality and country’s economial welfare in comparision with being in waiting list for live-donor and going into dialysis.

Keywords:
Kidney transplantation, Graft loss, Marginal donor