Abstract

A 58 year old male complaining from fatigue and enlargement of the spleen during last 3 years was admitted.His uncle had been undergone a splenectomy in his family history.There were the enlargement of spleen (15 cm from arcus costarum)and the liver (3cm from arcus costarum)on his examination.His laboratory findings were: Hb: 5.2gr,reticulocyte 41 %, 30 percent spherocytosis in periferal blood smear.Direct and indirect Coombs tests were negative.Glucose 6 phosphate dehydrogenase level was normal.There was increased activity of erythropoiesis in his bone marrow exam.Osmotic fragility of his erythrocytes has increased.He experienced no complication after splenectomy.