Abstract

Coronavirus 2019 disease (COVID-2019), which is triggered by acute respiratory syndrome coronavirus 2 (SARS-CoV-2), now continues widely as a pandemic. The virus was first detected in Wuhan, China in December 2019, and is known to have caused more than 27 000 deaths in 199 countries and more than 27,000 by the end of March 2020. Symptoms can be mostly mild but it may be in severe cases leading to widespread lung involvement and causing cytokine storms. Anti-viral and anti-HIV drugs, which are among the treatment options in severe clinical condition with diffuse lung involvement, may be beneficial but their effectiveness is not satisfactory. In patients who develop COVID-19 pneumonia and cytokine storm, different treatments are needed to improve symptoms and reduce mortality. In this article, besides anti-viral therapies, information on the mechanism and application of convalescent plasma (CP), immunoglobulin, IL-6 blockers and mesenchymal stem cell therapies, which may be useful in patients with COVID-19, will be presented.