Abstract

Non alcoholic Steatohepatitis is histologically identical to alcolohic liver disease and occurs most commonly in obesity, diabetes, jejunoileal bypass and drug ingestion (perhexilene maleate, aminodarone, corticosteroids and high doses of estrogens). Histological findings include large droplet fatty change, balooning of hepatocytes and usually Mallory bodies and neutrophylic infiltration. The pathogenesis of steatohepatitis is poorly understood. Its course is no rapid, but eventually progresses to cirrhosis.