Abstract

INTRODUCTION

Parathyroid neoplasms are tumors seen in about 0.1% of the population.Although parathyroid adenomas are the most common,carcinomas are also rarely seen.Our aim in this study is to evaluate the clinical, laboratory and histopathological characteristics of patients who underwent parathyroidectomy in our hospital in the last 5 years.

METHODS

156 patients who underwent parathyroidectomy in our hospital and examined in the pathology department were included in the study.The types of operations performed in cases were grouped as those who underwent only parathyroid excision and those who underwent thyroid partial/total excision with parathyroid excision.Age,gender, pre- and post-operative parathyroid hormone values, size,weight,pathological diagnosis of the parathyroid gland, presence of complications,comorbidities and clinical follow-up were evaluated.

RESULTS

84% of 156 cases were female,16% were male.The mean age is 53.82+13.49.The mean preoperative parathyroid hormone levels of the cases are 415.18+491.15 mg/dl, and the mean post-operative parathyroid hormone levels are 64.02+110.72 mg/dl.The mean volume of parathyroid tissues was calculated as 5.13+8.85 and the mean weight as 2.78+2.88 g. Pathological diagnoses are 83.3% adenoma,10.9% hyperplasia,2.6% atypical adenoma, 1.9% carcinoma, 0.6% normal parathyroid and 0.6% lymph node.It was observed that as the postoperative PTH level increased,the weight of the parathyroid gland increased and the lesion weight was higher in males.The addition of thyroidectomy to the treatment, conventional parathyroidectomy instead of the minimally invasive method,and the high size and volume of the parathyroid gland were found to be associated with complicated complications in the postoperative period.

DISCUSSION AND CONCLUSION

In terms of thyroid pathologies that may accompany,it will be more appropriate to evaluate preoperative cases in detail and to continue the treatment with minimally invasive methods for the comfort of the patient in postoperative processes.It is highly important to always take a multidisciplinary management in the approach to parathyroid masses and to evaluate the clinical, laboratory, intraoperative and pathological findings of the case together.