Abstract

19 patients with superficial bladder tumors, who had two or more tumor recurrences in a year or had 3 or more papillary tumors resected in one session were treated with intravesical Immun BCG Pasteur F (Institut Merieux 75 mg -1 cc - X2) weeldy for 6 weeks, after resection of all visible tumors. In a mean follow-up for 17,8 ± 6,5 months, 8 patients (% 42) had recurrences. 6 of these 8 patients were treated with a second course of BCG therapy after resection of ali visible tumors. 4 of them (% 67) had recurrences (mean follow-up 9,7 ± 8,4 months). Thus over-all response rate with two courses of prophylactic BCG therapy was % 68 (13 of 19 patients).