Abstract

AIM: Pseudomonas aeruginosa is an important nosocomial pathogen and the prevalance of multiple resistant isolates has been increasing. The aim of this study was to determine imipenem (IMP), cefoperazone / sulbactam (S-Sul), piperacillin/tazobactam (PIP/TZ) resistance patterns of P. aeruginosa in clinical specimens of patients in Anestesia intensive Care Unit. MATERIAL AND METHOD: Ninety-five P.aeruginosa strains isolated from various clinical specimens taken from the patients in our Anesthesia Intensive Care Ünite during 2007. Microorganisms were identified by conventional methods and VITEK 2 identification system. Antibiotic resistance were investigated by using E- test method and MIC 50 and MIC 90 values were calculated. FINDINGS: Resistance rates were found 39% to S-Sui, 41% FlP/TZ, 43% to IMP. MIC 50 and MIC 90 values were found 16-192, 32-192, 3-32 respectively CONCLUSION: This situation once again reveals that reasonable antibiotic usage mandatory. The local antibiotic susceptibility profıles of Pseudomonas spp. Should be surveyed continuously to avoid the spread of Intensive Care Unite isolates carrying high level antibiotic resistance.