The Effect of Maternal Socio-Demographic Status and First Trimester Screening Test in Predicting Term Stillbirth
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Clinical Research
VOLUME: 31 ISSUE: 2
P: 169 - 174
2021

The Effect of Maternal Socio-Demographic Status and First Trimester Screening Test in Predicting Term Stillbirth

Anatol J Gen Med Res 2021;31(2):169-174
1. Tepecik Education And Research Hospital, Clinic Of Obstetric And Gynecology, Izmir
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Received Date: 2019-11-14T09:20:38
Accepted Date: 2021-08-18T14:32:18
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Abstract

Objective: Stillbirth is defined by the World Health Organization as the complete birth of a fetal death baby. Stillbirth rate in Turkey is determined approximately 9.3/1000. Although many reasons have been identified in the etiology of stillbirth, idiopathic stillbirths are still detected. Currently, a cost-effective stillbirth screening strategy has not been recommended.

Methods: Term stillbirth cases that occurred in our clinic during 4 years period were investigated retrospectively. Pregnancies resulting in stillbirth and control group pregnancies were compared in terms of sociodemographic status and first trimester screening test results.

Results: Maternal age was found to be higher in the pregnancies resulting in stillbirth, while birth weight and gestational age were lower (p=0.003 and p<0.001 and p<0.001, respectively). There was no significant effect of maternal refugee status or income status on stillbirth. Pregnancy-related plasma protein A, one of the first trimester test markers, was not found to have an effect on predicting stillbirth, whereas low values of free beta-human chorionic gonadotrapine (BhCG) might have a role in predicting stillbirth (AUC 0.731 and p=0.006). Nuchal translucency (NT) was also found to be significant in predicting stillbirth but not as effective as free BhCG.

Conclusion: In our country, the stillbirth rate is almost twice that of developed countries. Free BhCG, NT, and maternal demographic data can be used to predict term stillbirths with often unknown causes.

Keywords:
stillbirth, PAPP-A, free Bhcg, NT, refugees