Abstract

AIM: It is well known that systemic infilammation impairs endothelial function. However, it is not clear whether uncomplicated percutaneus coronary intervention (PCI) causes endothelial dysfunction. The aim of this study was to investigate the effects of uncomplicated PCI on systemic inflammation and brachial artery flow mediated dilation (BAFMD) in patients with stable angina pectoris. MATETRIAL AND METHOD: Forty patients with stable angina pectoris (SAP), (30 male, 10 female, mean age: 56±10 years) with nonnal basal inflammation markers who had uncomplicated PCI were admitted to study. hs-CRP and BAFMD were measured before and 48 hours after PCI. RESULTS: There was a slight increase in hs-CRP levels after PCI (0,243 ± 0,105 vs 0,434 ± 0,130 mg/dl, p<0,0001). However, there were no statistically significant differences in BAFMD before and after PCI (%7,5 ±2,2 vs %7,1 ± 2,6, p>0,05). CONCLUSION: Although there were a slight increase in serum hs-CRP levels following uncomplicated percutaneous coronary intervention of patients with stable angina pectoris, brachial artery flow mediated dilation was not impaired.