Abstract

AIM: The rate of positive random biopsies taken during transurethral resection (TUR), the relationship between positive random biopsies and risk factors for superficial bladder cancer. The role of positive random biopsy findings on treatment approach were investigated. MATERIAL and METHOD: Between January 1994-June 1998,122 patients with superficial cancer were included in this study. Random biopsies were taken from each patient during the initial TUR. RESULTS: Mean age was 53 (24-82) Random biopsies were positive in 13 (11%) patients. There was no significant difference among stages in regard of positivity of random biopsies. Ten (77%) of 13 positive random biopsy sites were in close proximity to the initial lesion; the rest (%23) had showed different localizations. Intracavitary BCG was given if carcinoma in-situ (Cis) (53%) was found on random biopsies. In tumors reported as Grade 2 and superficial (Pt 1 management was changed according to risk factors (size, number). CONCLUSION: The finding of Cis and higher tumor grades on random biopsies changed our treatment in 70% of our patients and we strongly suggest to take random biopsy during the initial surgery.