Abstract

INTRODUCTION

Preoperative medication, involves the psychological and a pharmaceutical preparation of patients to surgical procedures. The postoperative effects of preoperative midazolam application were evaluated in this prospective, randomized, double-blind study in outpatient urologic surgery.

METHODS

64 male patients aged between 18-65 years undergoing daily urological surgery (varicocele, testicular sperm extraction, hydrocele) were included in the study. STAI test was performed in all patients prior to the operation room. 0.03 mg/kg midazolam was applied to the Group I 20 minutes before the surgical procedure, saline solution was applied to the Group 2. In the postoperative period vital signs, the degree of sedation (Ramsay Sedation Score), postoperative pain scores (VAS 0-10), side effects (nausea, vomiting) of the patients were recorded. Home readiness (PADSS ≥ 9) of patients was also recorded. Between 4-6 hours postoperatively, STAI test was performed again.

RESULTS

Groups were comparable with respect to demographic data and duration of surgery. Preoperative STAI values, postoperative Ramsay Sedation Scores were similar in both groups. Although postoperative STAI values were lower in group 1, the difference did not reach statistical significance. Time for home readiness was shorte in Group I. Postoperative pain scores in Group II was significantly higher than Group I.

DISCUSSION AND CONCLUSION

0.03 mg/kg iv midazolam given preoperatively reduced pain scores in the early postoperative period without prolonging recovery in patients undergoing daily urological surgery.