Abstract

In this experimental study. 24 rats (Mus. Norvegius Albinos) were used of which 12 were in the control group, and the other 12 in the therapeutic group. In the control group, portal vein thrombosis was created. By venous statis, and histological examinations were performed on the liver specimens, and liver function tests were also acquired for this group. In the therapeutic group, low dose streptokinase-3000 units (0.003 cc) was infused through the portal vein at which venous thrombosis had been produced experimentally. Ail the rats were sacrificed on the 7th postoperative day and histological liver examinations and biochemical studies were performed. According to the results there were no evidence of liver ischemia following the use of streptokinase.